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S Sivagurunathan
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C N Pagel
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L H Loh
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L C Wijeyewickrema Faculty of Veterinary Science, Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia

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R N Pike Faculty of Veterinary Science, Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010, Australia

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E J Mackie
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their precursors express two factors that are essential for osteoclast differentiation and activity: macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor κB ligand (RANKL) ( Ross 2008 ). Many factors that stimulate

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-12-0177
Volume/Issue:
Volume 50: Issue 3
Free access
Fabien Duval GIG – EA 7404, Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Unité de Formation et de Recherche des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France

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Esther Dos Santos GIG – EA 7404, Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Unité de Formation et de Recherche des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France
Service de Biologie Médicale, Centre Hospitalier de Poissy-Saint Germain, Poissy, France

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Hadia Moindjie GIG – EA 7404, Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Unité de Formation et de Recherche des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France

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Valérie Serazin GIG – EA 7404, Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Unité de Formation et de Recherche des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France
Service de Biologie Médicale, Centre Hospitalier de Poissy-Saint Germain, Poissy, France

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Nelly Swierkowski-Blanchard GIG – EA 7404, Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Unité de Formation et de Recherche des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France
Département de Biologie de la Reproduction, Cytogénétique, Gynécologie et Obstétrique, Centre Hospitalier de Poissy-Saint Germain, Poissy, France

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François Vialard GIG – EA 7404, Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Unité de Formation et de Recherche des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France
Département de Biologie de la Reproduction, Cytogénétique, Gynécologie et Obstétrique, Centre Hospitalier de Poissy-Saint Germain, Poissy, France

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Marie-Noëlle Dieudonné GIG – EA 7404, Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Unité de Formation et de Recherche des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France

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in a 5% CO 2 and 95% air atmosphere. When the cells reached confluence, they were cultured in the presence or absence of adiponectin (25 ng/mL and 250 ng/mL) in differentiation medium containing DMEM/F12 with E2 (10 –8  M), P4 (10 –6  M), charcoal

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-17-0046
Volume/Issue:
Volume 59: Issue 3
Open access
Giulia Cantini Endocrinology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

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Martina Trabucco Endocrinology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

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Alessandra Di Franco Endocrinology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

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Edoardo Mannucci Endocrinology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy
Azienda Ospedaliera Universitaria Careggi (AOUC), Careggi Hospital, Florence, Italy

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Michaela Luconi Endocrinology Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy
Azienda Ospedaliera Universitaria Careggi (AOUC), Careggi Hospital, Florence, Italy

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abdominal fat depots and characterized by our group ( Baglioni et al. 2009 , 2012 ), liraglutide and GLP-1 have recently been demonstrated to interfere with adipocyte proliferation and differentiation ( Cantini et al. 2015 , 2017 ), as further

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-19-0095
Volume/Issue:
Volume 63: Issue 4
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Yingdi Yuan Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China
Department of Pediatrics, The First People’s Hospital of Lianyungang, Xuzhou Medical University Affiliated Hospital of Lianyungang (Lianyungang Clinical College of Nanjing Medical University), Lianyungang, China

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Xinguo Cao Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China
Cancer Care Ontario, Toronto, Canada

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Jiaojiao Hu Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Jingyun Li Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Dan Shen Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Lianghui You Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Xianwei Cui Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Xing Wang Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Yahui Zhou Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Yao Gao Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Lijun Zhu Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Pengfei Xu Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Chenbo Ji Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Xirong Guo Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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Juan Wen Nanjing Maternity and Child Health Care Institute, Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China

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malignancy ( Haslam & James 2005 , Barth 2011 , Serra-Majem & Bautista-Castano 2013 ). What’s more, it is growing with alarming speed and is becoming a global public health crisis ( Ng et al. 2014 ). Adipocyte differentiation is a vital process for

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-18-0215
Volume/Issue:
Volume 62: Issue 3
Free access
Matthias S Dettmer Department of Pathology and Laboratory Medicine, Institute of Pathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Department of Pathology and Laboratory Medicine, Institute of Pathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA

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Aurel Perren Department of Pathology and Laboratory Medicine, Institute of Pathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA

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Holger Moch Department of Pathology and Laboratory Medicine, Institute of Pathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA

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Paul Komminoth Department of Pathology and Laboratory Medicine, Institute of Pathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA

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Yuri E Nikiforov Department of Pathology and Laboratory Medicine, Institute of Pathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA

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Marina N Nikiforova Department of Pathology and Laboratory Medicine, Institute of Pathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA

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Introduction Poorly differentiated (PD) thyroid carcinomas of conventional type and oncocytic (Hürthle) type (oPD) are biologically situated between well-differentiated papillary and follicular thyroid carcinomas (PTC and FTC respectively) on the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-13-0266
Volume/Issue:
Volume 52: Issue 2
Free access
Sandra Kuntz EA3442 Génétique, Signalisation, Différenciation, Université Henri Poincaré-Nancy I, Faculté des Sciences, BP 239, 54506 Vandoeuvre-lès-Nancy Cedex, France

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Amand Chesnel EA3442 Génétique, Signalisation, Différenciation, Université Henri Poincaré-Nancy I, Faculté des Sciences, BP 239, 54506 Vandoeuvre-lès-Nancy Cedex, France

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Stéphane Flament EA3442 Génétique, Signalisation, Différenciation, Université Henri Poincaré-Nancy I, Faculté des Sciences, BP 239, 54506 Vandoeuvre-lès-Nancy Cedex, France

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Dominique Chardard EA3442 Génétique, Signalisation, Différenciation, Université Henri Poincaré-Nancy I, Faculté des Sciences, BP 239, 54506 Vandoeuvre-lès-Nancy Cedex, France

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Introduction The urodele amphibian, Pleurodeles waltl , is an interesting model for the study of vertebrate sex differentiation because this phenomenon displays a genetic regulation which can be overridden by temperature in this

Article Type:
Research Article
DOI:
https://doi.org/10.1677/jme.1.01588
Volume/Issue:
Volume 33: Issue 3
Free access
Huixia Li Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Hui Meng Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Min Xu Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Xin Gao Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Xulei Sun Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Xinxin Jin Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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Hongzhi Sun Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China

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, accompanied by reduced bone length ( Takarada et al. 2012 ) and impaired chondrocyte differentiation ( Ma et al. 2019 ). Noticeably, global Bmal1 -null mice had a low bone mass phenotype not only in limb bones ( Takarada et al. 2012 , Samsa et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-22-0181
Volume/Issue:
Volume 70: Issue 4
Restricted access
Laurent Léotoing Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Michèle Manin Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Didier Monté Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Silvère Baron Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Yves Communal Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Corinne Lours Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Georges Veyssière Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Laurent Morel Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Claude Beaudoin Génétique des Eucaryotes et Endocrinologie Moléculaire, UMR 6547 CNRS, Equipe Physiologie Comparée et Endocrinologie Moléculaire, Université Blaise Pascal, Campus Universitaire des Cézeaux, 24 Avenue des Landais, 63177 Aubière Cedex, France
UMR 8161 Institut de Biologie de Lille/CNRS/Université de Lille 1/Université Lille2/Institut Pasteur de Lille, 1 rue Calmette, BP 447, 59021 Lille Cedex, France
Laboratoire d’Immunologie, Centre Jean Perrin, 58 rue Montalembert, BP 392, 63011 Clermont-Ferrand, France

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Introduction Androgens mediate a wide range of physiological responses in the male reproductive system. They also play a critical role in the development and differentiation of the urogenital tract and especially in the functional

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-07-0021
Volume/Issue:
Volume 39: Issue 2
Free access
Silvia Senesi Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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Paola Marcolongo Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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Ivana Manini Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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Rosella Fulceri Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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Vincenzo Sorrentino Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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Miklós Csala Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy
Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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Gábor Bánhegyi Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy
Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy
Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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Angelo Benedetti Department of Pathophysiology, Molecular Medicine Section, Department of Medical Chemistry, Pathobiochemistry Research Group of the Hungarian Academy of Sciences, Experimental Medicine and Public Health, University of Siena, Via A. Moro no. 1, 53100 Siena, Italy

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, Odermatt et al . 2006 ). It was demonstrated that mutations in genes of both HSD11B1 and H6PD in a triallelic digenic model of inheritance result in the loss of HSD11B1 reductase activity ( Draper et al . 2003 ). During the differentiation of human

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JME-08-0028
Volume/Issue:
Volume 41: Issue 3
Free access
Ji Seon Park Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Su Jung Bae Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea
Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Sik-Won Choi Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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You Hwa Son Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Sung Bum Park Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea
Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Sang Dal Rhee Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Hee Youn Kim Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Won Hoon Jung Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Seung Kyu Kang Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Jin Hee Ahn Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Seong Hwan Kim Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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Ki Young Kim Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea
Division of Drug Discovery Research, Division of Life and Pharmaceutical Sciences and Center for Cell Signaling and Drug Discovery Research, Laboratory of Translational Therapeutics, Department of Toxicology, Department of Medicinal and Pharmaceutical Chemistry, Korea Research Institute of Chemical Technology, PO Box 107, Yuseong-gu, Daejeon 305-600, Republic of Korea

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limit cell proliferation in preadipocytes ( Tomlinson et al . 2006 ). Mature adipocytes express late differentiation genes involved in lipid metabolism and lipid transport, and many of these genes are regulated by glucocorticoids ( Wu et al . 1996

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JME-13-0177
Volume/Issue:
Volume 52: Issue 2
Free access